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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCRS1
All Species:
36.06
Human Site:
Y243
Identified Species:
66.11
UniProt:
Q96EZ8
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96EZ8
NP_001012300.1
462
51803
Y243
H
R
H
P
D
A
F
Y
L
A
R
T
A
K
A
Chimpanzee
Pan troglodytes
XP_509047
513
57528
Y294
H
R
H
P
D
A
F
Y
L
A
R
T
A
K
A
Rhesus Macaque
Macaca mulatta
XP_001109790
462
51406
Y243
H
R
H
P
D
A
F
Y
L
A
R
T
A
K
A
Dog
Lupus familis
XP_850537
462
51831
Y243
H
R
H
P
D
A
F
Y
L
A
R
T
A
K
A
Cat
Felis silvestris
Mouse
Mus musculus
Q99L90
462
51674
Y243
H
T
H
P
D
A
F
Y
L
A
R
T
A
K
A
Rat
Rattus norvegicus
NP_001013124
462
51804
Y243
H
R
H
P
D
A
F
Y
L
A
R
T
A
K
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512056
254
28409
D80
K
Q
Y
Y
L
L
E
D
Q
T
V
Q
P
L
P
Chicken
Gallus gallus
XP_001232507
447
50517
L248
Q
L
M
K
Q
Y
Y
L
L
D
D
Q
T
V
Q
Frog
Xenopus laevis
NP_001080873
453
50959
Y234
N
K
H
P
E
V
F
Y
M
S
R
T
A
K
S
Zebra Danio
Brachydanio rerio
NP_998438
472
53117
Y253
N
K
H
P
N
V
F
Y
P
S
R
T
A
K
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647852
578
63519
Y355
D
K
N
A
S
V
F
Y
C
A
R
T
A
K
S
Honey Bee
Apis mellifera
XP_624688
469
53205
Y252
E
A
N
A
H
T
F
Y
S
A
R
T
A
K
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797067
874
96141
N657
N
K
H
S
T
V
F
N
P
M
R
T
A
K
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90
94.1
99.1
N.A.
98.2
98.4
N.A.
45
85.2
82
75.4
N.A.
44.6
51.5
N.A.
33.9
Protein Similarity:
100
90
94.5
99.3
N.A.
98.4
98.6
N.A.
48
90.9
90
86.2
N.A.
59
69.5
N.A.
43.1
P-Site Identity:
100
100
100
100
N.A.
93.3
100
N.A.
0
6.6
53.3
53.3
N.A.
46.6
53.3
N.A.
40
P-Site Similarity:
100
100
100
100
N.A.
93.3
100
N.A.
13.3
13.3
93.3
80
N.A.
66.6
60
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
16
0
47
0
0
0
62
0
0
85
0
54
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
47
0
0
8
0
8
8
0
0
0
0
% D
% Glu:
8
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
85
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% G
% His:
47
0
70
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
31
0
8
0
0
0
0
0
0
0
0
0
85
0
% K
% Leu:
0
8
0
0
8
8
0
8
54
0
0
0
0
8
0
% L
% Met:
0
0
8
0
0
0
0
0
8
8
0
0
0
0
0
% M
% Asn:
24
0
16
0
8
0
0
8
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
62
0
0
0
0
16
0
0
0
8
0
8
% P
% Gln:
8
8
0
0
8
0
0
0
8
0
0
16
0
0
8
% Q
% Arg:
0
39
0
0
0
0
0
0
0
0
85
0
0
0
0
% R
% Ser:
0
0
0
8
8
0
0
0
8
16
0
0
0
0
16
% S
% Thr:
0
8
0
0
8
8
0
0
0
8
0
85
8
0
0
% T
% Val:
0
0
0
0
0
31
0
0
0
0
8
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
8
0
8
8
77
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _